Human OSBP2 activation kit by CRISPRa

CAT#: GA108492

OSBP2 CRISPRa kit - CRISPR gene activation of human oxysterol binding protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: OSBP2
• Locus ID: 23762
• Kit Components:

  GA108492G1, OSBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108492G2, OSBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108492G3, OSBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001003812, NM_001282738, NM_001282739, NM_001282740, NM_001282741, NM_001282742, NM_030758
• UniProt ID: Q969R2
• Synonyms: ORP-4; ORP4; OSBPL1; OSBPL4
• Summary: The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013]