Human EDC4 activation kit by CRISPRa

CAT#: GA108456

EDC4 CRISPRa kit - CRISPR gene activation of human enhancer of mRNA decapping 4

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: EDC4
• Locus ID: 23644
• Kit Components:

  GA108456G1, EDC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108456G2, EDC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108456G3, EDC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014329
• UniProt ID: Q6P2E9
• Synonyms: Ge-1; GE1; HEDL5; HEDLS; RCD-8; RCD8
• Summary: In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).[UniProtKB/Swiss-Prot Function]