Human LDOC1 activation kit by CRISPRa

CAT#: GA108454

LDOC1 CRISPRa kit - CRISPR gene activation of human LDOC1 regulator of NFKB signaling

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LDOC1
• Locus ID: 23641
• Kit Components:

  GA108454G1, LDOC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108454G2, LDOC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108454G3, LDOC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012317
• UniProt ID: O95751
• Synonyms: BCUR1; Mar7; Mart7
• Summary: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008]