Human KCNE1L (KCNE5) activation kit by CRISPRa

CAT#: GA108446

KCNE5 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily E regulatory subunit 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KCNE5
• Locus ID: 23630
• Kit Components:

  GA108446G1, KCNE1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108446G2, KCNE1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108446G3, KCNE1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012282
• UniProt ID: Q9UJ90
• Synonyms: KCNE1L
• Summary: This gene encodes a member of a family of single pass transmembrane domain proteins that function as ancillary subunits to voltage-gated potassium channels. Members of this family affect diverse processes in potassium channel regulation, including ion selectivity, voltage dependence, and anterograde recycling from the plasma membrane. Variants of this gene are associated with idiopathic ventricular fibrillation and Brugada syndrome. [provided by RefSeq, Nov 2016]