Human MMD activation kit by CRISPRa

CAT#: GA108374

MMD CRISPRa kit - CRISPR gene activation of human monocyte to macrophage differentiation associated

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MMD
• Locus ID: 23531
• Kit Components:

  GA108374G1, MMD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108374G2, MMD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108374G3, MMD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012329, N40480
• UniProt ID: Q15546
• Synonyms: MMA; MMD1; PAQR11
• Summary: This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]