Human GGA3 activation kit by CRISPRa

CAT#: GA108085

GGA3 CRISPRa kit - CRISPR gene activation of human golgi associated, gamma adaptin ear containing, ARF binding protein 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GGA3
• Locus ID: 23163
• Kit Components:

  GA108085G1, GGA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA108085G2, GGA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA108085G3, GGA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001172703, NM_001172704, NM_001291641, NM_001291642, NM_014001, NM_138619, NR_033345
• UniProt ID: Q9NZ52
• Synonyms: KIAA0154
• Summary: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]