Human KIF3A activation kit by CRISPRa

CAT#: GA107652

KIF3A CRISPRa kit - CRISPR gene activation of human kinesin family member 3A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KIF3A
• Locus ID: 11127
• Kit Components:

  GA107652G1, KIF3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107652G2, KIF3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107652G3, KIF3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300791, NM_001300792, NM_007054
• UniProt ID: Q9Y496
• Synonyms: FLA10; KLP-20
• Summary: Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.[UniProtKB/Swiss-Prot Function]