Human IGF2BP2 activation kit by CRISPRa

CAT#: GA107294

IGF2BP2 CRISPRa kit - CRISPR gene activation of human insulin like growth factor 2 mRNA binding protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: IGF2BP2
• Locus ID: 10644
• Kit Components:

  GA107294G1, IGF2BP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107294G2, IGF2BP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107294G3, IGF2BP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007225, NM_001291869, NM_001291872, NM_001291873, NM_001291874, NM_001291875, NM_006548, NR_138486
• UniProt ID: Q9Y6M1
• Synonyms: IMP-2; IMP2; VICKZ2
• Summary: This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]