Human JWA (ARL6IP5) activation kit by CRISPRa

CAT#: GA107210

ARL6IP5 CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor like GTPase 6 interacting protein 5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ARL6IP5
• Locus ID: 10550
• Kit Components:

  GA107210G1, JWA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107210G2, JWA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107210G3, JWA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006407
• UniProt ID: O75915
• Synonyms: addicsin; DERP11; GTRAP3-18; hp22; HSPC127; jmx; JWA; PRAF3
• Summary: Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. [provided by RefSeq, Jul 2008]