Human Aly (ALYREF) activation kit by CRISPRa

CAT#: GA106921

ALYREF CRISPRa kit - CRISPR gene activation of human Aly/REF export factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ALYREF
• Locus ID: 10189
• Kit Components:

  GA106921G1, Aly gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106921G2, Aly gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106921G3, Aly gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005782, NR_158770
• UniProt ID: Q86V81
• Synonyms: ALY; ALY/REF; BEF; REF; THOC4
• Summary: The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]