Human SERF2 activation kit by CRISPRa

CAT#: GA106908

SERF2 CRISPRa kit - CRISPR gene activation of human small EDRK-rich factor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SERF2
• Locus ID: 10169
• Kit Components:

  GA106908G1, SERF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106908G2, SERF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106908G3, SERF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018108, NM_001199875, NM_001199876, NM_001199877, NM_001199878, NM_005770, NR_037672
• UniProt ID: P84101
• Synonyms: 4F5REL; FAM2C; H4F5REL; HsT17089
• Summary: Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760). Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (PubMed:20723760).[UniProtKB/Swiss-Prot Function]