Human Arp3 (ACTR3) activation kit by CRISPRa

CAT#: GA106846

ACTR3 CRISPRa kit - CRISPR gene activation of human actin related protein 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ACTR3
• Locus ID: 10096
• Kit Components:

  GA106846G1, Arp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106846G2, Arp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106846G3, Arp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277140, NM_005721, NR_102318
• UniProt ID: P61158
• Synonyms: ARP3
• Summary: The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]