Human FLASH (CASP8AP2) activation kit by CRISPRa
CAT#: GA106767
CASP8AP2 CRISPRa kit - CRISPR gene activation of human caspase 8 associated protein 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
USD 1,665.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CASP8AP2 |
Locus ID | 9994 |
Kit Components | GA106767G1, FLASH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106767G2, FLASH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106767G3, FLASH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001137667, NM_001137668, NM_012115 |
UniProt ID | Q9UKL3 |
Synonyms | CED-4; FLASH; RIP25 |
Summary | This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN424342 | CASP8AP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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