Human FARP2 activation kit by CRISPRa

CAT#: GA106646

FARP2 CRISPRa kit - CRISPR gene activation of human FERM, ARH/RhoGEF and pleckstrin domain protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: FARP2
• Locus ID: 9855
• Kit Components:

  GA106646G1, FARP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106646G2, FARP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106646G3, FARP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282983, NM_001282984, NM_014808
• UniProt ID: O94887
• Synonyms: FIR; FRG; PLEKHC3
• Summary: Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).[UniProtKB/Swiss-Prot Function]