Human Rho GTPase activating protein 29 (ARHGAP29) activation kit by CRISPRa

CAT#: GA106281

ARHGAP29 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 29

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ARHGAP29
• Locus ID: 9411
• Kit Components:

  GA106281G1, Rho GTPase activating protein 29 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106281G2, Rho GTPase activating protein 29 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106281G3, Rho GTPase activating protein 29 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001328664, NM_001328665, NM_001328666, NM_001328667, NM_004815
• UniProt ID: Q52LW3
• Synonyms: PARG1
• Summary: Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]