Human GRHPR activation kit by CRISPRa

CAT#: GA106260

GRHPR CRISPRa kit - CRISPR gene activation of human glyoxylate and hydroxypyruvate reductase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GRHPR
• Locus ID: 9380
• Kit Components:

  GA106260G1, GRHPR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106260G2, GRHPR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106260G3, GRHPR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012203
• UniProt ID: Q9UBQ7
• Synonyms: GLXR; GLYD; PH2
• Summary: This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]