Human S1PR2 activation kit by CRISPRa

CAT#: GA106197

S1PR2 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate receptor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: S1PR2
• Locus ID: 9294
• Kit Components:

  GA106197G1, S1PR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106197G2, S1PR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106197G3, S1PR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004230
• UniProt ID: O95136
• Synonyms: AGR16; EDG-5; EDG5; Gpcr13; H218; LPB2; S1P2
• Summary: This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]