Human Claudin 12 (CLDN12) activation kit by CRISPRa
CAT#: GA106032
CLDN12 CRISPRa kit - CRISPR gene activation of human claudin 12
Find the corresponding CRISPRi Inhibitor Kit
USD 1,657.00
2 Weeks*
USD 850.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CLDN12 |
Locus ID | 9069 |
Kit Components | GA106032G1, Claudin 12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106032G2, Claudin 12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106032G3, Claudin 12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001185072, NM_001185073, NM_012129 |
UniProt ID | P56749 |
Summary | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011] |
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Other Versions
SKU | Description | Size | Price |
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KN409820 | CLDN12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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