Human IQGAP1 activation kit by CRISPRa

CAT#: GA105870

IQGAP1 CRISPRa kit - CRISPR gene activation of human IQ motif containing GTPase activating protein 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: IQGAP1
• Locus ID: 8826
• Kit Components:

  GA105870G1, IQGAP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105870G2, IQGAP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105870G3, IQGAP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003870
• UniProt ID: P46940
• Synonyms: HUMORFA01; p195; SAR1
• Summary: This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]