Human CCNK activation kit by CRISPRa

CAT#: GA105856

CCNK CRISPRa kit - CRISPR gene activation of human cyclin K

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CCNK
• Locus ID: 8812
• Kit Components:

  GA105856G1, CCNK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105856G2, CCNK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105856G3, CCNK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099402, NM_003858
• UniProt ID: O75909
• Synonyms: CPR4
• Summary: The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008]