Human LIPF activation kit by CRISPRa

CAT#: GA105629

LIPF CRISPRa kit - CRISPR gene activation of human lipase F, gastric type

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: LIPF
• Locus ID: 8513
• Kit Components:

  GA105629G1, LIPF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105629G2, LIPF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105629G3, LIPF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198828, NM_001198829, NM_001198830, NM_004190
• UniProt ID: P07098
• Synonyms: GL; HGL; HLAL
• Summary: This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]