Human Peregrin (BRPF1) activation kit by CRISPRa

CAT#: GA105340

BRPF1 CRISPRa kit - CRISPR gene activation of human bromodomain and PHD finger containing 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: BRPF1
• Locus ID: 7862
• Kit Components:

  GA105340G1, Peregrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105340G2, Peregrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105340G3, Peregrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001003694, NM_001319049, NM_001319050, NM_004634, NR_160918
• UniProt ID: P55201
• Synonyms: BR140
• Summary: This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. This protein binds to the catalytic MYST domains of the MOZ and MORF proteins and may play a role in stimulating acetyltransferase and transcriptional activity of the complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]