Human UBA52 activation kit by CRISPRa

CAT#: GA105034

UBA52 CRISPRa kit - CRISPR gene activation of human ubiquitin A-52 residue ribosomal protein fusion product 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: UBA52
• Locus ID: 7311
• Kit Components:

  GA105034G1, UBA52 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105034G2, UBA52 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105034G3, UBA52 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033930, NM_003333, NM_001321017, NM_001321018, NM_001321019, NM_001321020, NM_001321021, NM_001321022
• UniProt ID: P62987
• Synonyms: CEP52; HUBCEP52; L40; RPL40
• Summary: Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008]