Human Transferrin (TF) activation kit by CRISPRa

CAT#: GA104827

TF CRISPRa kit - CRISPR gene activation of human transferrin

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TF
• Locus ID: 7018
• Kit Components:

  GA104827G1, Transferrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104827G2, Transferrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104827G3, Transferrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001063, NM_001354703, NM_001354704
• UniProt ID: P02787
• Synonyms: HEL-S-71p; PRO1557; PRO2086; TFQTL1
• Summary: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]