Human TCF20 activation kit by CRISPRa

CAT#: GA104791

TCF20 CRISPRa kit - CRISPR gene activation of human transcription factor 20

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TCF20
• Locus ID: 6942
• Kit Components:

  GA104791G1, TCF20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104791G2, TCF20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104791G3, TCF20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005650, NM_181492
• UniProt ID: Q9UGU0
• Synonyms: AR1; SPBP; TCF-20
• Summary: This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]