Human SPRR1A activation kit by CRISPRa

CAT#: GA104598

SPRR1A CRISPRa kit - CRISPR gene activation of human small proline rich protein 1A

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SPRR1A
• Locus ID: 6698
• Kit Components:

  GA104598G1, SPRR1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104598G2, SPRR1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104598G3, SPRR1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199828, NM_005987
• UniProt ID: P35321
• Synonyms: SPRK
• Summary: Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.[UniProtKB/Swiss-Prot Function]