Human Spermine synthase (SMS) activation kit by CRISPRa

CAT#: GA104524

SMS CRISPRa kit - CRISPR gene activation of human spermine synthase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SMS
• Locus ID: 6611
• Kit Components:

  GA104524G1, Spermine synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104524G2, Spermine synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104524G3, Spermine synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258423, NM_004595
• UniProt ID: P52788
• Synonyms: MRSR; SPMSY; SpS; SRS
• Summary: This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]