Human epithelial Sodium Channel gamma (SCNN1G) activation kit by CRISPRa

CAT#: GA104305

SCNN1G CRISPRa kit - CRISPR gene activation of human sodium channel epithelial 1 gamma subunit

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: SCNN1G
• Locus ID: 6340
• Kit Components:

  GA104305G1, epithelial Sodium Channel gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104305G2, epithelial Sodium Channel gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104305G3, epithelial Sodium Channel gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039
• UniProt ID: P51170
• Synonyms: BESC3; ENaCg; ENaCgamma; PHA1; SCNEG
• Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009]