Human RS1 activation kit by CRISPRa

CAT#: GA104233

RS1 CRISPRa kit - CRISPR gene activation of human retinoschisin 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RS1
• Locus ID: 6247
• Kit Components:

  GA104233G1, RS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104233G2, RS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104233G3, RS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000330
• UniProt ID: O15537
• Synonyms: RS; XLRS1
• Summary: This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008]