Human PPP2R2C activation kit by CRISPRa

CAT#: GA103721

PPP2R2C CRISPRa kit - CRISPR gene activation of human protein phosphatase 2 regulatory subunit Bgamma

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PPP2R2C
• Locus ID: 5522
• Kit Components:

  GA103721G1, PPP2R2C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103721G2, PPP2R2C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103721G3, PPP2R2C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206994, NM_001206995, NM_001206996, NM_020416, NM_181876, NM_001363388
• UniProt ID: Q9Y2T4
• Synonyms: B55-GAMMA; IMYPNO; IMYPNO1; PR52; PR55G
• Summary: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]