Human PP2A-alpha (PPP2CA) activation kit by CRISPRa

CAT#: GA103715

PPP2CA CRISPRa kit - CRISPR gene activation of human protein phosphatase 2 catalytic subunit alpha

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: PPP2CA
• Locus ID: 5515
• Kit Components:

  GA103715G1, PP2A-alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103715G2, PP2A-alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103715G3, PP2A-alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002715, NM_001355019, NR_149151
• UniProt ID: P67775
• Synonyms: PP2Ac; PP2CA; PP2Calpha; RP-C
• Summary: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]