Human NME2 activation kit by CRISPRa

CAT#: GA103223

NME2 CRISPRa kit - CRISPR gene activation of human NME/NM23 nucleoside diphosphate kinase 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NME2
• Locus ID: 4831
• Kit Components:

  GA103223G1, NME2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103223G2, NME2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103223G3, NME2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018137, NM_001018138, NM_001018139, NM_001198682, NM_002512
• UniProt ID: P22392
• Synonyms: NDKB; NDPK-B; NDPKB; NM23-H2; NM23B; PUF
• Summary: Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010]