Human Necdin (NDN) activation kit by CRISPRa

CAT#: GA103122

NDN CRISPRa kit - CRISPR gene activation of human necdin, MAGE family member

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: NDN
• Locus ID: 4692
• Kit Components:

  GA103122G1, Necdin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103122G2, Necdin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103122G3, Necdin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002487
• UniProt ID: Q99608
• Synonyms: HsT16328; PWCR
• Summary: This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons. [provided by RefSeq, Jul 2008]