Human MMP19 activation kit by CRISPRa

CAT#: GA102947

MMP19 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 19

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MMP19
• Locus ID: 4327
• Kit Components:

  GA102947G1, MMP19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102947G2, MMP19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102947G3, MMP19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032360, NM_001272101, NM_002429, NM_022790, NM_022791, NM_022792, NR_073606
• UniProt ID: Q99542
• Synonyms: matrix metallopeptidase 19; matrix metalloproteinase 18; matrix metalloproteinase 19; MMP18; MMP18, RASI-1; RASI-1
• Summary: This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]