Human MCC activation kit by CRISPRa

CAT#: GA102840

MCC CRISPRa kit - CRISPR gene activation of human MCC regulator of WNT signaling pathway

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MCC
• Locus ID: 4163
• Kit Components:

  GA102840G1, MCC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102840G2, MCC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102840G3, MCC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001085377, NM_002387
• UniProt ID: P23508
• Synonyms: MCC1
• Summary: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]