Human IRS1 activation kit by CRISPRa

CAT#: GA102459

IRS1 CRISPRa kit - CRISPR gene activation of human insulin receptor substrate 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: IRS1
• Locus ID: 3667
• Kit Components:

  GA102459G1, IRS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102459G2, IRS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102459G3, IRS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005544
• UniProt ID: P35568
• Synonyms: HIRS-1
• Summary: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]