Human INSL3 activation kit by CRISPRa

CAT#: GA102440

INSL3 CRISPRa kit - CRISPR gene activation of human insulin like 3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: INSL3
• Locus ID: 3640
• Kit Components:

  GA102440G1, INSL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102440G2, INSL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102440G3, INSL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001265587, NM_005543
• UniProt ID: P51460
• Synonyms: ley-I-L; RLF; RLNL
• Summary: This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]