Human HOXA5 activation kit by CRISPRa

CAT#: GA102187

HOXA5 CRISPRa kit - CRISPR gene activation of human homeobox A5

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: HOXA5
• Locus ID: 3202
• Kit Components:

  GA102187G1, HOXA5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102187G2, HOXA5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102187G3, HOXA5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019102
• UniProt ID: P20719
• Synonyms: HOX1; HOX1.3; HOX1C
• Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]