Human HDGF activation kit by CRISPRa

CAT#: GA102091

HDGF CRISPRa kit - CRISPR gene activation of human heparin binding growth factor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: HDGF
• Locus ID: 3068
• Kit Components:

  GA102091G1, HDGF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102091G2, HDGF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102091G3, HDGF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001126050, NM_001126051, NM_001319186, NM_001319187, NM_001319188, NM_004494, NR_135008
• UniProt ID: P51858
• Synonyms: HMG1L2
• Summary: This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016]