Human GNAI3 activation kit by CRISPRa

CAT#: GA101846

GNAI3 CRISPRa kit - CRISPR gene activation of human G protein subunit alpha i3

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GNAI3
• Locus ID: 2773
• Kit Components:

  GA101846G1, GNAI3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101846G2, GNAI3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101846G3, GNAI3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006496
• UniProt ID: P08754
• Synonyms: 87U6; ARCND1
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]