Human DHODH activation kit by CRISPRa

CAT#: GA101195

DHODH CRISPRa kit - CRISPR gene activation of human dihydroorotate dehydrogenase (quinone)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DHODH
• Locus ID: 1723
• Kit Components:

  GA101195G1, DHODH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101195G2, DHODH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101195G3, DHODH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025193, NM_001361
• UniProt ID: Q02127
• Synonyms: DHOdehase; dihydroorotate dehydrogenase; dihydroorotate oxidase; human complement of yeast URA1
• Summary: The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]