Human DMXL1 activation kit by CRISPRa

CAT#: GA101170

DMXL1 CRISPRa kit - CRISPR gene activation of human Dmx like 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: DMXL1
• Locus ID: 1657
• Kit Components:

  GA101170G1, DMXL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101170G2, DMXL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101170G3, DMXL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001290321, NM_001290322, NM_005509, NM_001349239, NM_001349240
• UniProt ID: Q9Y485
• Summary: The protein encoded by this gene is a member of the WD repeat superfamily of proteins, which have regulatory functions. This gene is expressed in many tissue types including several types of eye tissue, and it has been associated with ocular phenotypes. In addition, it is upregulated in cultured cells that overexpress growth factor independence 1B, a transcription factor that is essential for hematopoietic cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]