Human CD151 activation kit by CRISPRa

CAT#: GA100698

CD151 CRISPRa kit - CRISPR gene activation of human CD151 molecule (Raph blood group)

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CD151
• Locus ID: 977
• Kit Components:

  GA100698G1, CD151 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100698G2, CD151 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100698G3, CD151 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039490, NM_004357, NM_139029, NM_139030, NM_139031
• UniProt ID: P48509
• Synonyms: GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24
• Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]