Human CCKBR activation kit by CRISPRa

CAT#: GA100622

CCKBR CRISPRa kit - CRISPR gene activation of human cholecystokinin B receptor

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CCKBR
• Locus ID: 887
• Kit Components:

  GA100622G1, CCKBR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100622G2, CCKBR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100622G3, CCKBR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000731, NM_001318029, NM_176875, NM_001363552
• UniProt ID: P32239
• Synonyms: CCK-B; CCK2R; GASR
• Summary: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015]