Human CFAP410 activation kit by CRISPRa

CAT#: GA100524

CFAP410 CRISPRa kit - CRISPR gene activation of human cilia and flagella associated protein 410

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CFAP410
• Locus ID: 755
• Kit Components:

  GA100524G1, CFAP410 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100524G2, CFAP410 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100524G3, CFAP410 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271440, NM_001271441, NM_001271442, NM_004928
• UniProt ID: O43822
• Synonyms: LRRC76; YF5/A2
• Summary: Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012]