Human ATP12A activation kit by CRISPRa

CAT#: GA100336

ATP12A CRISPRa kit - CRISPR gene activation of human ATPase H+/K+ transporting non-gastric alpha2 subunit

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: ATP12A
• Locus ID: 479
• Kit Components:

  GA100336G1, ATP12A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100336G2, ATP12A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100336G3, ATP12A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001185085, NM_001676
• UniProt ID: P54707
• Synonyms: #945; ATP1AL1; HK
• Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]