Oma1 (NM_001106669) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR214961L3V

Lenti ORF particles, Oma1 (Myc-DDK-tagged ORF) - Rat OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (Oma1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Oma1
• Synonyms: RGD1304821
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001106669
• ORF Size: 1512 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR214961).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001106669.1, NP_001100139.1
• RefSeq Size: 1839 bp
• RefSeq ORF: 1515 bp
• Locus ID: 298282
• UniProt ID: D3ZS74
• Cytogenetics: 5q33
• Gene Summary: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.[UniProtKB/Swiss-Prot Function]