Hsph1 (NM_001011901) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR213187L4V

Lenti ORF particles, Hsph1 (GFP-tagged ORF) - Rat heat shock 105kDa/110kDa protein 1 (Hsph1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Hsph1
• Synonyms: Hsp105
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001011901
• ORF Size: 2574 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR213187).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001011901.1, NP_001011901.1
• RefSeq Size: 3453 bp
• RefSeq ORF: 2577 bp
• Locus ID: 288444
• UniProt ID: Q66HA8
• Cytogenetics: 12p11
• Gene Summary: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.[UniProtKB/Swiss-Prot Function]