Ptges3 (NM_001130989) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR212140L4V

Lenti ORF particles, Ptges3 (GFP-tagged ORF) - Rat prostaglandin E synthase 3 (cytosolic) (Ptges3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Ptges3
• Synonyms: RGD1561913
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001130989
• ORF Size: 480 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR212140).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001130989.1, NP_001124461.1
• RefSeq Size: 1691 bp
• RefSeq ORF: 483 bp
• Locus ID: 362809
• UniProt ID: P83868
• Cytogenetics: 7q11
• Gene Summary: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (By similarity).[UniProtKB/Swiss-Prot Function]