March2 (NM_001034108) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR207729L3V

Lenti ORF particles, March2 (Myc-DDK-tagged ORF) - Rat membrane-associated ring finger (C3HC4) 2 (March2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: March2
• Synonyms: MARCH-II; RGD1306395
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001034108
• ORF Size: 738 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR207729).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001034108.1, NP_001029280.1
• RefSeq Size: 1306 bp
• RefSeq ORF: 741 bp
• Locus ID: 362849
• UniProt ID: Q5I0I2
• Cytogenetics: 7q13
• Gene Summary: E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.[UniProtKB/Swiss-Prot Function]